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Chapter-32 New Delivery for Classical Drugs: Intrauterine or Intravaginal

BOOK TITLE: Endometriosis: Current Management and Future Trends

Author
1. Petraglia Felice
2. Luisi Stefano
ISBN
9788184488081
DOI
10.5005/jp/books/11032_32
Edition
1/e
Publishing Year
2010
Pages
6
Author Affiliations
1. University of Siena, Siena, Italy
2. University of Siena, Siena, Italy
Chapter keywords

Abstract

In the recent years, new treatments for endometriosis have been investigated. Following the recent evidences that hormonal treatment by vaginal or intrauterine route are becoming of current use for hormonal postmenopausal replacement treatment, contraception or menorrhagia, the administration of progestins, such as levonorgestrel and danazol, answers to some problems related to the long-term management of endometriosis. A case-control study, the vaginal administration of a gel containing danazol (100 mg/day in 0.2 ml) for four months effectively reduced dysmenorrhea and chronic pelvic pain related to endometriosis in 24 women.

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