The chapter starts with basics of bonding like explaining about types of bonding, surface energy and requirements for bonding to tooth structure. The chapter next deals in detail about enamel bonding, etching, types of enamel etching pattern. Dentin bonding is explained in detail and also a detailed discussion about classification of dentin bonding agents is outlined. Concept of hybridization and Wet vs. Dry bonding is explained. The chapter concludes with explanation about amalgam bonding, glass ionomer bonding, and ceramic bonding. Final section deals with pit and fissure sealant, it’s mechanism of adhesion and clinical application.