Gestational trophoblastic neoplasia is highly curable. Best results will not be achieved unless these cases are referred promptly to specialized centers where appro­priate facilities are available to determine the correct diagnosis, the extent of the disease and where optimal care during chemotherapy is available. Gestational trophoblastic neoplasia (GTN) encompasses a spectrum of clinical and histological entities and comprises a group of neoplastic disorders arising from trophoblastic tissue of the placenta. GTN is a common gynecological problem in Malaysia and other South-East Asian countries. Due to the lack of a Tumor Register in many of these countries, the true incidence is unknown.