Central Nervous System and Cardiovascular Diseases - Review Article
Author Maurizio Arduini
ISSN 0973-614X
JournalTitle Donald School Journal of Ultrasound in Obstetrics and Gynecology
DOI 10.5005/jp-journals-10009-1544
Volume 11
Issue 4
Publishing Year 2017
Pages 362-366
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Children with congenital heart diseases (CHD) are at increased risk of neurodevelopmental delay (NDD). In fetuses with CHD, blood streaming in the brain may be partially deoxygenated. Signs of cerebrovascular autoregulation comparable to the “brain-sparing effect” in growth-restricted fetuses may be shown in fetuses with CHD depending on the type of heart disease. This effect appears to be predominantly present in fetuses with left-side obstructive lesions (LSOL). During prenatal counseling, it is recommended to mention the possibility of an increased risk of NDD. The severity of this impairment varies from the type of CHD, being highest up to 40 to 45% in lesions with univentricular heart hemodynamics, such as hypoplastic left heart syndrome (HLHS). The prenatal life plays an important role in determining postnatal neurodevelopmental functions, but the severity of NDD in fetuses with CHD cannot be predicted prenatally.

Keywords: Brain sparing effect, Congenital heart diseases, Neurodevelopmental delay.

How to cite this article: Arduini M. Central Nervous System and Cardiovascular Diseases. Donald School J Ultrasound Obstet Gynecol 2017;11(4):362-366.

Source of support: Nil

Conflict of interest: None

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