Mucociliary Function: Its Variations with Disease - Original Article
Author Hemanth Vamanshankar, Satish C Kumar, AP Preetham, Musarrat Feshan
ISSN 0974-4630
JournalTitle Clinical Rhinology An International Journal
DOI 10.5005/jp-journals-10013-1271
Volume 9
Issue 2
Publishing Year 2016
Pages 68-73
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ABSTRACT

Introduction: This study compares the nasal mucociliary clearance time of patients with chronic sinusitis (pre- and postoperatively) and smokers, with controls, attending the ear, nose, and throat outpatient department at Southern Railway Headquarters Hospital, Perambur, Chennai.

Materials and methods: Saccharin granule was used to study mucociliary clearance as it is safe, easy, fast, and reliable. A total of 32 patients in each group were studied. In chronic rhinosinusitis patients, the test was done preoperatively and 4 weeks postoperatively.

Results: The average mucociliary clearance time pre- and postoperatively in chronic rhinosinusitis patients was 29.54 ± 28.68 and 12.17 ± 5.84 respectively. Cigarette smokers had a longer mucociliary clearance time (27.63 ± 21.11) compared with beedi smokers (24.04 ± 24.93). Controls had the fastest mucociliary clearance rate of 9.67 ± 4.62 among the study subjects.

Conclusion: Surgery for chronic rhinosinusitis improves both the overall symptoms of chronic rhinosinusitis and the protective functions of the nose and paranasal sinuses. Smokers had an impaired clearance rate compared with normals. As age advances, the mucociliary clearance rate becomes slower.

Keywords: Chronic rhinosinusitis, Mucociliary clearance, Sacchain, Smokers.

How to cite this article: Vamanshankar H, Kumar SC, Preetham AP, Feshan M. Mucociliary Function: Its Variations with Disease. Clin Rhinol An Int J 2016;9(2):68-73.

Source of support: Nil

Conflict of interest: None

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